特工斯特拉顿(多米尼克·库珀 Dominic Cooper 饰)的同事马蒂(泰勒·霍奇林 Tyler Hoechlin 饰)在一次任务中不幸丧生。斯特拉顿就此得知一名叛逃了的前苏联特工巴罗夫斯基(托马斯·克莱舒曼 Thomas Kretschmann 饰)拥有一批极为危险的生化武器,如今,他企图用这批生化武器来事实他的复仇大计。 为了阻止巴罗夫斯基的阴谋,斯特拉顿来到了罗马。汉克(奥斯汀·斯托维尔 Austin Stowell 饰)是马蒂最好的朋友,亦是行动小队中的一员,仇恨冲昏了他的头脑,他的失误导致整个行动计划失败了,巴罗夫斯基从他们的眼皮子底下逃之夭夭。一行人只得再度回到伦敦,重新计划,留给他们的时间不多了。
Based on the novel by Karel Capek, the prominent Czech writer of the early 20th century who coined the word robot for his play R.U.R., the story revolves around a discovery of Krakatit - a powerful explosive - by Prokop, an experimental scientist who, following an accidental explosion in his lab, slips in and out of delirium. When he realises that, in a delirious period, he has given the formula for making Krakatit to one of his colleagues, he tries to find the man, who does not realize how dangerous a thing Krakatit is. In the process, he nearly gives his discovery away again to foreign interests, a group of anarchists, and even greater forces of darkness...